Autism spectrum disorder (ASD) is a neurodevelopmental disorder that has been increasing in worldwide prevalence,1 including Singapore.In this latest issue of the Annals, we share the latest Singapore Clinical Practice Guidelines (CPG) for Autism in Children and Adolescents, discussed by Wong et al.2 This is the culmination of the tremendous effort
Genome-wide screening for genes whose deletions confer sensitivity to mutagenic purine base analogs in yeast
Abstract Background N-hydroxylated base analogs, such as 6-hydroxylaminopurine (HAP) and 2-amino-6-hydroxylaminopurine (AHA), are strong mutagens in various organisms due to their ambiguous base-pairing Nutritional Bars properties.The systems protecting cells from HAP and related noncanonical purines in Escherichia coli include specialized deoxyrib